IV Therapy Beyond the Hangover Cure: What the Science Actually Says

Walk past any wellness clinic in a major city and you will see IV drip stations. The marketing often leans into recovery — hangovers, jet lag, post-workout fatigue. And while IV hydration absolutely works for those purposes, it sells the therapy short.

At Rejuvenate & Wellness Center, IV therapy is a clinical tool. The formulations we use are designed around specific physiological goals, and the evidence behind them is more substantial than most people realize.

Why IV Delivery Is Different From Oral Supplementation

When you take a vitamin orally, it passes through your digestive system. Absorption is limited by gut health, first-pass liver metabolism, and bioavailability ceilings. Vitamin C, for example, has an oral bioavailability of roughly 50% at moderate doses, dropping to under 20% at high doses.

The Core IV Formulations We Use

Myers' Cocktail — The Foundation

The Myers' Cocktail, developed by physician John Myers in the 1970s and refined by Alan Gaby, MD, is the most studied IV nutrient formulation. It contains magnesium, calcium, B vitamins (B1, B2, B3, B5, B6, B12), and vitamin C. A 2009 pilot study in the Journal of Alternative and Complementary Medicine found significant improvements in fibromyalgia symptoms. Broader clinical use has shown benefit for fatigue, migraines, seasonal allergies, and acute infections.

High-Dose Vitamin C — Immune and Antioxidant Support

Vitamin C at high doses (10–25g IV) achieves plasma concentrations that are simply not achievable orally. Clinical applications include immune support during acute illness, post-surgical recovery, and skin health — vitamin C is essential for collagen synthesis, and IV delivery supports skin quality from the inside out.

NAD+ — The Longevity Protocol

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell of your body, essential for energy production, DNA repair, neurological function, and metabolic regulation. NAD+ levels decline by approximately 50% between ages 40 and 60.

Immunity Drip — Acute and Preventive Support

Our Immunity formulation combines high-dose vitamin C, zinc, B vitamins, and glutathione. It is designed for acute illness, pre-travel immune loading, high-stress periods when cortisol suppresses immune function, and seasonal transitions — particularly fall and spring when respiratory illness peaks in Central Florida.

Glutathione — The Master Antioxidant

Glutathione is produced naturally by the liver, but production declines with age, chronic illness, and environmental toxin exposure. IV glutathione neutralizes free radicals, supports liver detoxification, improves skin clarity and tone, and enhances the efficacy of other IV nutrients. Oral glutathione has poor bioavailability — IV delivery is the only reliable way to raise systemic levels meaningfully.

Bariatric Support — For Post-Surgical Patients

Patients who have undergone bariatric surgery face significant nutritional absorption challenges. Our Bariatric IV formulation addresses deficiencies in B12, iron, calcium, and vitamin D — providing nutrients in a form that bypasses the compromised absorption pathway entirely.

Who Benefits Most From IV Therapy?

What to Expect at Your First IV Appointment

A typical IV session at Rejuvenate & Wellness Center takes 30–90 minutes depending on the formulation. You will complete a brief intake, have your vitals checked, and receive your IV in a comfortable, private setting. Most patients notice effects within a few hours. NAD+ infusions may produce more gradual effects over 24–48 hours.

We offer single sessions and membership packages for patients who benefit from regular infusions. Our IV Best Sellers — NAD+ ($175), Immunity ($150), and Bariatric ($165) — are available at both our Orlando and Kissimmee locations.

Clinically Reviewed & Supervised

Marc Pierre-Louis, FNP-BC

Founder & CEO · Family Nurse Practitioner

FNP-BC since 2011 with 15+ years in ER, cardiology, neurology, and internal medicine. Passionate about medical weight loss, hormone replacement therapy, stem cell therapy, and peptide protocols — bringing the full power of regenerative and metabolic medicine to every patient.

Tamara Nieves-Alicea, FNP-BC

COO · Family Nurse Practitioner

ER RN since 2009, FNP-BC since 2017. Passionate about HRT, joint injections, and skin health — including melasma and hyperpigmentation treatment. Brings clinical precision and cultural sensitivity to every aesthetic and wellness visit.

Every treatment at Rejuvenate & Wellness Center is designed, reviewed, and supervised by our board-certified providers — meet the team →